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BCT2029

Chemical Structure : BCT2029

CAS No.: 3079354-66-5

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BCT2029 (BCT-2029)

Catalog No.: PC-27395Not For Human Use, Lab Use Only.

BCT2029 is a potent Biliverdin IXb reductase (BLVRB, biliverdin reductase IXβ) inhibitor, inhibits BLVRB reductive activity using both FMN (flavin mononucleotide, IC50=194 nM) and DCPIP (2,6-dichlorophenolindophenol; IC50=28 nM) as substrates.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BCT2029 is a potent Biliverdin IXb reductase (BLVRB, biliverdin reductase IXβ) inhibitor, inhibits BLVRB reductive activity using both FMN (flavin mononucleotide, IC50=194 nM) and DCPIP (2,6-dichlorophenolindophenol; IC50=28 nM) as substrates.

Physicochemical Properties

M.Wt 359.39
Formula C21H17N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(3-ethyl-7-oxo-2-phenyl-1,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)benzoic acid

References

1. Rahul Raghavan Thekke Veedu, et al. J Med Chem. 2026 Jul 27. doi: 10.1021/acs.jmedchem.6c01466.

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