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BDM43124

Chemical Structure : BDM43124

CAS No.: 1333227-75-0

BDM43124

Catalog No.: PC-26431Not For Human Use, Lab Use Only.

BDM43124 is the methyl ester precursor of BDM43079, which is a selective inhibitor of insulin degrading enzyme (IDE) with IC50 of 0.1 uM, inhibits the hydrolysis of amyloid-β1-40 by IDE in in SH-SY5Y cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BDM43124 is the methyl ester precursor of BDM43079, which is a selective inhibitor of insulin degrading enzyme (IDE) with IC50 of 0.1 uM, inhibits the hydrolysis of amyloid-β1-40 by IDE in in SH-SY5Y cells.

Physicochemical Properties

M.Wt 415.49
Formula C21H29N5O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

((((S)-2-(1H-Imidazol-4-yl)-1-methylcarbamoyl-ethylcarbamoyl)-methyl)-(3-phenyl-propyl)-amino)-acetic acid methyl ester

References

1. Julie Charton, et al. Eur J Med Chem. 2015 Jan 27:90:547-67.

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