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Chemical Structure : BDP-13176
CAS No.: 2290660-61-4
Catalog No.: PC-21071Not For Human Use, Lab Use Only.
BDP-13176 is a small molecule inhibitor of actin-bundling protein Fascin-1 (Fscn1) with SPR and ITC Kd values of 85 and 50 nM, respectively, inhibits fascin-mediated actin bundling with IC50 of 240 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $388 | In stock | |
| 25 mg | $598 | In stock | |
| 100 mg | Get quote |
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BDP-13176 is a small molecule inhibitor of actin-bundling protein Fascin-1 (Fscn1) with SPR and ITC Kd values of 85 and 50 nM, respectively, inhibits fascin-mediated actin bundling with IC50 of 240 nM.
BDP-13176 is a useful chemical probe for fascin's potential role in tumor invasion and metastasis.
| M.Wt | 497.38 | |
| Formula | C24H22Cl2N6O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1H-Pyrazolo[4,3-c]pyridine-7-carboxamide, 5-[(3,4-dichlorophenyl)methyl]-4,5-dihydro-4-oxo-1-(4-piperidinyl)-N-4-pyridinyl- |
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1. Stuart Francis, et al. Bioorg Med Chem Lett. 2019 Apr 15;29(8):1023-1029.
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