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BI-0314

Chemical Structure : BI-0314

CAS No.: 2244560-46-9

BI-0314 (BI0314;BI 0314)

Catalog No.: PC-35665Not For Human Use, Lab Use Only.

BI-0314 (BI0314) is an allosteric activator of protein tyrosine phosphatase non-receptor type 5 (PTPN5, STEP) with potency of 56% at 500 uM, displays no activity against hPTP1B and hTCPTP..

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    Biological Activity

    BI-0314 (BI0314) is an allosteric activator of protein tyrosine phosphatase non-receptor type 5 (PTPN5, STEP) with potency of 56% at 500 uM, displays no activity against hPTP1B and hTCPTP.

    Physicochemical Properties

    M.Wt 286.302
    Formula C13H17F3N4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-(3-(piperidin-4-yl)-5-(trifluoromethyl)phenyl)guanidine

    References

    1. Tautermann CS, et al. J Med Chem. 2018 Sep 12. doi: 10.1021/acs.jmedchem.8b00857.

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