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Chemical Structure : BI-1935
CAS No.: 940954-41-6
Catalog No.: PC-63248Not For Human Use, Lab Use Only.
BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $368 | In stock | |
| 25 mg | Get quote | ||
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM.
BI-1935 is also highly active in a cellular Hep G2-DHET assay format with IC50 of <1 nM.
BI-1935 can also be used in vivo and showed a dose dependent effect on mean arterial pressure blood pressure in Dahl salt sensitive rats.
BI-1935 also shows good selectivity against hCYP epoxygenases 2J2/2C9/2C19 and IL-2.
| M.Wt | 498.466 | |
| Formula | C24H21F3N6O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1-(2-ethoxyethyl)-6-oxo-N-(5-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin-2-yl)-1,6-dihydropyridine-3-carboxamide |
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1. Patent WO2007067836A2.
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