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BIO101

Chemical Structure : BIO101

CAS No.: 5289-74-7

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BIO101 (20-hydroxyecdysone, Crustecdysone)

Catalog No.: PC-22028Not For Human Use, Lab Use Only.

BIO101 (20-hydroxyecdysone, Crustecdysone) is a small molecule agonist of Mas receptor (MasR), has anti-inflammatory, anti-fibrotic and cardioprotective properties, shows potential treatment for respiratory failure in COVID-19.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BIO101 (20-hydroxyecdysone, Crustecdysone) is a small molecule agonist of Mas receptor (MasR), has anti-inflammatory, anti-fibrotic and cardioprotective properties, shows potential treatment for respiratory failure in COVID-19.

Physicochemical Properties

M.Wt 480.64
Formula C27H44O7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-((2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-6H-cyclopenta[a]phenanthren-6-one

References

1. Serova M, et al. J Cachexia Sarcopenia Muscle. 2024 Feb;15(1):55-66.

2. Latil M, et al. Drug Discov Today. 2021 May;26(5):1311-1318.

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