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Chemical Structure : BIO 8898
Catalog No.: PC-62356Not For Human Use, Lab Use Only.
BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM.
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BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM; inhibits CD40L-dependent apoptosis in a cellular assay.
| M.Wt | 909.145 | |
| Formula | C53H64N8O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Silvian LF, et al. ACS Chem Biol. 2011 Jun 17;6(6):636-47.
2. Ganesan L, et al. Pharmazie. 2012 May;67(5):374-9.
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