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Chemical Structure : BMS-986205
CAS No.: 1923833-60-6
Catalog No.: PC-60068Not For Human Use, Lab Use Only.
BMS-986205 (Linrodostat, F-001287, ONO-7701) is a novel potent, selective and orally available IDO1 inhibitor with IC50 of 1.1 nM in cell-based assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 25 mg | $348 | In stock | |
| 100 mg | $988 | In stock | |
| 500 mg | Get quote |
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BMS-986205 (Linrodostat, F-001287, ONO-7701) is a novel potent, selective and orally available IDO1 inhibitor with IC50 of 1.1 nM in cell-based assays; has no inhibitory activity on TDO, potently inhibits kynurenine (kyn) production in IDO1-HEK293 cells with IC50 of 1.1 nM; shows potential with superior PD properties and support further evaluation in combination with vivo.
Skin Cancer
Phase 2 Clinical
| M.Wt | 410.912 | |
| Formula | C24H24ClFN2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2R)-N-(4-Chlorophenyl)-2-[cis-4-(6-fluoro-4-quinolinyl)cyclohexyl]propanamide |
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