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BMS-986339

Chemical Structure : BMS-986339

CAS No.: 2477873-64-4

BMS-986339

Catalog No.: PC-47028Not For Human Use, Lab Use Only.

BMS-986339 is a potent, selective farnesoid X receptor (FXR) agonist with EC50 of 34 nM (hFXR-Gal4), demonstrates differential induction of Fgf15 in the liver and ileum by FXR agonists in vivo.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BMS-986339 is a potent, selective farnesoid X receptor (FXR) agonist with EC50 of 34 nM (hFXR-Gal4), demonstrates differential induction of Fgf15 in the liver and ileum by FXR agonists in vivo.

Physicochemical Properties

M.Wt 643.724
Formula C35H41F4N3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

1. Susheel J Nara, et al. J Med Chem. 2022 Jun 15. doi: 10.1021/acs.jmedchem.2c00165.

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