Cat. No. |
Product Name |
Information |
PC-38044 |
EDP-305
|
EDP-305 (EDP305) is a potent, selective, nonbile acid farnesoid X receptor (FXR) agonist with antifibrotic effect. |
PC-61390 |
Nidufexor
FXR agonist
|
Nidufexor (LMB763, LMB-763) is a potent, selective, non-bile acid partial agonist of farnesoid X receptor (FXR) with EC50 of 7 nM in FXR-HTRF biochemical assay measuring the ligand-induced interaction between FXR and the Steroid Receptor Coactivator-1 (SRC1). |
PC-61368 |
Cilofexor
FXR agonist
|
Cilofexor (GS-9674, GS9674, PX-104) is a potent, specific, non-steroidal farnesoid X receptor (FXR) agonist with EC50 of 43 nM. |
PC-61057 |
DM509
|
DM509 is a potent, orally active dual modulator of FXR and soluble epoxide hydrolase (sEH) that exertss partial FXR agonism (pEC50=7.7) and sEH inhibitory activity (pIC50=8.4). |
PC-60080 |
GSK-2324
FXR agonist
|
GSK-2324 (GSK2324) is a potent, selective, full FXR agonist with EC50 of 120 nM in FRET assay. |
PC-60079 |
LY-2562175
FXR agonist
|
LY-2562175 (LY2562175, LY 2562175) is a novel potent, selective, partial FXR agonist with EC50 of 193 nM. |
PC-60056 |
Tropifexor
FXR agonist
|
Tropifexor (LJN-452, LJN452) is a novel highly potent, selective, orally acitive FXR full agonist with EC50 of 0.26 nM. |
PC-45825 |
GW-4064
FXR agonist
|
GW-4064 (GW4064) is a potent and selective FXR agonist with EC50 of 15 nM in cell-free assay, >200-fold more potent than CDCA. |
PC-42924 |
INT-747
|
INT-747(Obeticholic acid, 6-ECDCA, 6-Ethylchenodeoxycholic acid) is a potent and selective FXR agonist (EC50=99 nM). |
PC-21879 |
ID166
FXR agonist
|
ID119031166 (ID166) is a novel potent, selective FXR agonist with EC50 of 3 nM and 5 nM in TR-FRET FXR co-activator assay and FXR reporter assay, respectively. |
PC-20980 |
HPG1860
FXR agonist
|
HPG1860 is a potent, selective, nonbile acid full FXR agonist with EC50 of 5 nM and 18 nM in FR-FRET and luciferase assays, respectively. |
PC-20979 |
MET409
FXR agonist
|
MET409 (MET-409) is a potent, selective farnesoid X receptor (FXR) agonist with EC50 of 16 nM (human FXR). |