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BMT-052

Chemical Structure : BMT-052

CAS No.: 1628720-84-2

BMT-052 (BMT052;BMT 052)

Catalog No.: PC-60424Not For Human Use, Lab Use Only.

A second generation, orally biovailable pan-genotypic HCV NS5B polymerase inhibitor with EC50 of 1-10 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A second generation, orally biovailable pan-genotypic HCV NS5B polymerase inhibitor with EC50 of 1-10 nM; exhibits good genotype coverage, low clearance, a moderate volume of distribution and no cytotoxicity (CC50>100 uM).

Physicochemical Properties

M.Wt 635.6235
Formula C30H17D9F4N6O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-(5-((2-(1,2,4-oxadiazol-3-yl)propan-2-yl-1,1,1,3,3,3-d6)carbamoyl)-6-(methoxy-d3)pyridin-3-yl)-2-(4-fluorophenyl)-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide

References

1. Parcella K, et al. ACS Med Chem Lett. 2017 Jun 29;8(7):771-774.

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