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BMT-090605

Chemical Structure : BMT-090605

CAS No.: 1551403-51-0

BMT-090605 (BMT 090605;BMT090605)

Catalog No.: PC-60636Not For Human Use, Lab Use Only.

BMT-090605 (BMT 090605, BMT090605) is a potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50 0.6 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BMT-090605 (BMT 090605, BMT090605) is a potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50 0.6 nM.
    BMT-090605 weakly inhibits BIKE and GAK with IC50 of 45 and 60 nM, respectively.

    Physicochemical Properties

    M.Wt 364.449
    Formula C21H24N4O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-8-((2-amino-4-methylpentyl)oxy)-4,6-dimethyl-5-oxo-5,6-dihydrobenzo[c][2,7]naphthyridine-9-carbonitrile

    References

    1. Kostich W, et al. J Pharmacol Exp Ther. 2016 Sep;358(3):371-86.

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