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Chemical Structure : BRD8518
Catalog No.: PC-38411Not For Human Use, Lab Use Only.
BRD8518 is a specific small molecule TRIB1 inducer, modulates expression of the key genes involved in VLDL production and in LDL clearance in HepG2 cells.
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BRD8518 is a specific small molecule TRIB1 inducer, modulates expression of the key genes involved in VLDL production and in LDL clearance in HepG2 cells.
BRD8518 activity is MEK1/2 dependent and the treatment of HepG2 cells with BRD8518 stimulates ERK1/2 phosphorylation.
| M.Wt | 607.630 | |
| Formula | C33H32F3N3O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nagiec MM, et al. Medchemcomm. 2018 Sep 14;9(11):1831-1842.
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