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Chemical Structure : BSJ-03-123
CAS No.: 2361493-16-3
Catalog No.: PC-35936Not For Human Use, Lab Use Only.
BSJ-03-123 is a potent, CDK6-selective small-molecule degrader (PROTAC) that uniquely enables rapid pharmacological interrogation of CDK6-dependent functions.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $488 | In stock | |
| 100 mg | Get quote |
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BSJ-03-123 is a potent, CDK6-selective small-molecule degrader (PROTAC) that uniquely enables rapid pharmacological interrogation of CDK6-dependent functions.
BSJ-03-123 induces differential E3 ligase recruitment and ensuing degradation of CDK6, but not CDK4.
| M.Wt | 936.036 | |
| Formula | C48H57N9O11 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(2-(2-(2-(2-(4-(6-((3-acetyl-1-cyclopentyl-4-methyl-2-oxo-1,2-dihydro-1,6-naphthyridin-7-yl)amino)pyridin-3-yl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide |
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1. Brand M, et al. Cell Chem Biol. 2018 Nov 22. pii: S2451-9456(18)30413-6. doi: 10.1016/j.chembiol.2018.11.006.
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