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Chemical Structure : BTZO-15
Catalog No.: PC-35109Not For Human Use, Lab Use Only.
BTZO-15 is an active BTZO-1 derivative for ARE-activation with a favorable ADME-Tox profile, induces expression of heme oxygenase-1 (HO-1) and inhibits NO-induced cell death in IEC-18 cells.
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BTZO-15 is an active BTZO-1 derivative for ARE-activation with a favorable ADME-Tox profile, induces expression of heme oxygenase-1 (HO-1) and inhibits NO-induced cell death in IEC-18 cells; induces HO-1 expression in the rectum and attenuates DSS-induced changes, reduces the ulcerated area and rectal MPO activity in TNBS-induced colitis rats without affecting rectal TNF-α levels; orally active.
| M.Wt | 424.87 | |
| Formula | C17H13ClN2O5S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yukitake H, et al. PLoS One. 2011;6(8):e23256.
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