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Chemical Structure : BW-031 iodide
Catalog No.: PC-47030Not For Human Use, Lab Use Only.
BW-031 iodide is a potent cationic sodium channel inhibitor, inhibited Nav 1.7 (IC50=9.5 uM) and Nav 1.1 channels with approximately sixfold greater potency than QX-314.
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BW-031 iodide is a potent cationic sodium channel inhibitor, inhibited Nav 1.7 (IC50=9.5 uM) and Nav 1.1 channels with approximately sixfold greater potency than QX-314.
BW-031 inhibited inflammatory pain in guinea pig model of citric acid-induced cough.
BW-031 produced more effective and longer-lasting inhibition of pain than QX-314 in the mouse UV burn model.
| M.Wt | 430.374 | |
| Formula | C19H31IN2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ivan Tochitsky, et al. Br J Pharmacol. 2021 Oct;178(19):3905-3923.
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