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Chemical Structure : Befotertinib
CAS No.: 1835667-63-4
Catalog No.: PC-38341Not For Human Use, Lab Use Only.
Befotertinib (D-0316) is an orally active, third-generation EGFR tyrosine kinase inhibitor that is selective for both EGFR-TKI sensitizing and T790M resistance mutations in NSCLC.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $218 | In stock | |
| 25 mg | $398 | In stock | |
| 100 mg | $858 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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Befotertinib (D-0316) is an orally active, third-generation EGFR tyrosine kinase inhibitor that is selective for both EGFR-TKI sensitizing and T790M resistance mutations in NSCLC.
| M.Wt | 567.617 | |
| Formula | C29H32F3N7O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-(2,2,2-trifluoroethyl)-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide |
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1. Nagasaka M, et al. J Thorac Oncol. 2021 May;16(5):740-763.
2. Jian H, et al. Oncologist. 2022 Mar 11;27(3):163-e213.
3. Shun Lu, et al. Cancer Res (2021) 81 (13_Supplement): CT170.
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