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Chemical Structure : Benvitimod
Catalog No.: PC-60054Not For Human Use, Lab Use Only.
A natural aryl hydrocarbon receptor (AhR) agonist with anti-inflammatory properties.
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A natural aryl hydrocarbon receptor (AhR) agonist with anti-inflammatory properties; binds and activates AhR in multiple cell types, moderates proinflammatory cytokine expression in stimulated peripheral blood CD4+ T cells and ex vivo human skin, and impacts barrier gene expression in primary human keratinocytes; shows no impact on imiquimod-induced skin inflammation in AhR-deficient mice.
Psoriasis
Phase 3 Clinical
| M.Wt | 254.329 | |
| Formula | C17H18O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bissonnette R, et al. Arch Dermatol. 2010 Apr;146(4):446-9.
2. Bissonnette R, et al. J Eur Acad Dermatol Venereol. 2012 Dec;26(12):1516-21.
3. Smith SH,et al. J Invest Dermatol. 2017 Oct;137(10):2110-2119.
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