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Berberrubine chloride

Chemical Structure : Berberrubine chloride

CAS No.: 15401-69-1

Berberrubine chloride

Catalog No.: PC-26063Not For Human Use, Lab Use Only.

Berberrubine chloride is an orally active metabolite of berberine, alleviates mucosal lesions and inflammation in mouse colitis models, inhibits TDP-43 aggregation and shows anti-inflammatory, anti-tumor, and antiviral activities.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Berberrubine chloride is an orally active metabolite of berberine, alleviates mucosal lesions and inflammation in mouse colitis models, inhibits TDP-43 aggregation and shows anti-inflammatory, anti-tumor, and antiviral activities.

Physicochemical Properties

M.Wt 357.79
Formula C19H16ClNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

9-Hydroxy-10-methoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride

References

1. Lo CY, et al. Bioorg Med Chem Lett. 2013 Jan 1;23(1):305-9.

2. Yu XT, et al. PLoS One. 2018 Mar 14;13(3):e0194069.

3. Kapsiani S, et al. bioRxiv [Preprint]. 2026 Feb 13:2026.02.12.705375.

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