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Chemical Structure : Betrixaban
CAS No.: 330942-05-7
Catalog No.: PC-42505Not For Human Use, Lab Use Only.
A highly potent, selective Factor Xa inhibitor with Ki/IC50 of 0.117 nM/1.5 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $112 | In stock | |
| 50 mg | $256 | In stock | |
| 100 mg | $440 | In stock |
Bulk size, bulk discount!
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A highly potent, selective Factor Xa inhibitor with Ki/IC50 of 0.117 nM/1.5 nM; no significant activity against thrombin, plasmin, tPA, activated protein C, and kallikrein; exhibts weak binding affinity for hERG (Ki=0.42 uM); orally efficacious.
Thrombosis
Phase 3 Clinical
| M.Wt | 451.9055 | |
| Formula | C23H22ClN5O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 22 mg/mL |
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| Chemical Name/SMILES |
Benzamide, N-(5-chloro-2-pyridinyl)-2-[[4-[(dimethylamino)iminomethyl]benzoyl]amino]-5-methoxy- |
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1. Zhang P, et al. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2179-85.
2. Cohen AT, et al. Am Heart J. 2014 Mar;167(3):335-41.
3. Cohen AT, et al. N Engl J Med. 2016 Aug 11;375(6):534-44.
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