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Chemical Structure : Boceprevir
CAS No.: 394730-60-0
Catalog No.: PC-42477Not For Human Use, Lab Use Only.
A potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $120 | In stock | |
| 50 mg | $200 | In stock | |
| 100 mg | $280 | In stock |
Bulk size, bulk discount!
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A potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays; displays >2000-fold selectivity over human neutrophil elastase (HNE).
HCV Infection
Approved
| M.Wt | 519.6767 | |
| Formula | C27H45N5O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 10 mg/mL |
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| Chemical Name/SMILES |
3-Azabicyclo[3.1.0]hexane-2-carboxamide, N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-, (1R,2S,5S)- |
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1. Venkatraman S, et al. J Med Chem. 2006 Oct 5;49(20):6074-86.
2. Sarrazin C, et al. Gastroenterology. 2007 Apr;132(4):1270-8.
3. Flint M, et al. Antimicrob Agents Chemother. 2009 Feb;53(2):401-11.
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