Brinzolamide | CA II inhibitor | Probechem Biochemicals

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Chemical Structure : Brinzolamide

CAS No.: 138890-62-7

Brinzolamide (AL-4862, AL4862)

Catalog No.: PC-24455Not For Human Use, Lab Use Only.

Brinzolamide (AL-4862) is a potent, selective carbonic anhydrase II (CA II) inhibitor with IC50 of 3.2 nM, reduces intraocular pressure (IOP) by inhibiting ciliary CA-II and decreasing atrial fluid secretion.

Packing	Price	Stock
25 mg	$48	In stock
50 mg	$68	In stock
100 mg	$108	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	383.50
Formula	C12H21N3O5S3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (4R)-

References

1. Vatsala Naageshwaran, et al. J Pharm Sci. 2021 Jan;110(1):529-535.

2. Ilies M, et al. Bioorg Med Chem. 2000 Aug;8(8):2145-55.

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Brinzolamide (AL-4862, AL4862)

Biological Activity

Physicochemical Properties

References

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