| Cat. No. |
Product Name |
Information |
| PC-62314 |
Indisulam
Carbonic Anhydrase inhibitor
|
Indisulam (E7070) is potent, sulfonamide, carbonic anhydrase inhibitor that possesses antiproliferative activities, causes decrease in the S phase fraction along with G1 and/or G2 accumulation in various cancer cell lines. |
| PC-70028 |
SLC-0111
CA IX/CA XII inhibitor
|
SLC-0111 (U-104) is a sulfonamide carbonic anhydrase (CA, EC 4.2.1.1) inhibitor with IC50 of 45 nM and 4.5 nM for tumor-associated enzymes hCA IX and hCA XII. |
| PC-25270 |
FC-531
Carbonic anhydrase inhibitor
|
FC-531 is a highly potent carbonic anhydrase (CA) inhibitor with Ki values of 6.2 nM and 2.3 nM for the transmembrane and tumor-associated isoforms CA IX and CA XII. |
| PC-24459 |
Dichlorophenamide
Carbonic anhydrase inhibitor
|
Dichlorophenamide is a potent carbonic anhydrase inhibitor with Ki values of 1200, 38, 1500, 50 and 50 nM for isozymes hCA I, hCA II, hCA IV, hCA IX, and hCA XII respectively. |
| PC-24458 |
Ethoxzolamide
Carbonic anhydrase inhibitor
|
Ethoxzolamide is a potent carbonic anhydrase inhibitor with Ki values of 25, 8, 93, 34 and 22 nM for isozymes hCA I, hCA II, hCA IV, hCA IX, and hCA XII respectively. |
| PC-24457 |
Methazolamide
CA II inhibitor
|
Methazolamide (L584601) is a potent, BBB-penatrable and orally active carbonic anhydrase inhibitor with Ki of 14 nM for human carbonic anhydrase II (CA II). |
| PC-24456 |
Dorzolamide hydrochloride
CA II inhibitor
|
Dorzolamide hydrochloride (L671152) is a potent, selective carbonic anhydrase II (CA II) inhibitor with IC50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. |
| PC-24455 |
Brinzolamide
CA II inhibitor
|
Brinzolamide (AL-4862) is a potent, selective carbonic anhydrase II (CA II) inhibitor with IC50 of 3.2 nM, reduces intraocular pressure (IOP) by inhibiting ciliary CA-II and decreasing atrial fluid secretion. |
| PC-24454 |
Carbonic anhydrase inhibitor C18
CAS 215998-88-2
|
Carbonic anhydrase inhibitor C18 is a potent carbonic anhydrase inhibitor with Ki values of 4000, 21, 60, 14 and 7.0 nM for isozymes hCA I, hCA II, hCA IV, hCA IX, and hCA XII respectively. |
| PC-23741 |
VD11-4-2
CA IX inhibitor
|
VD11-4-2 is a high affinity, selectivity inhibitor of carbonic anhydrase IX (CA IX) with ITC Kd of 15 pM, with remarkable selectivity over other CA isozymes. |
| PC-23740 |
AZ19-3-1
CA IX inhibitor
|
AZ19-3-2 is a high affinity, selective inhibitor of carbonic anhydrase IX (CA IX) with binding Kd of 250 pM in thermal shift assays. |
| PC-23739 |
AZ19-3-2
CA IX inhibitor
|
AZ19-3-2 is a high affinity, dual-head inhibitor of carbonic anhydrase IX (CA IX) with binding Kd of 25 pM in thermal shift assays, binds two CA IX catalytic domains on the cell surface simultaneously. |
