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Chemical Structure : C105SR
Catalog No.: PC-21262Not For Human Use, Lab Use Only.
C105SR is small-molecule cyclophilin inhibitor with IC50 of 5 nM for inhibition of CypD PPIase activity and 9 nM for mitochondrial swelling.
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C105SR is small-molecule cyclophilin inhibitor with IC50 of 5 nM for inhibition of CypD PPIase activity and 9 nM for mitochondrial swelling.
C105SR inhibits mPTP opening and prevented cell death in a model of hypoxia/reoxygenation.
C105SR protects against hepatic IRI in vivo by reducing hepatocyte necrosis and apoptosis.
| M.Wt | 633.61 | |
| Formula | C32H33BrN4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Amel Kheyar, et al. JHEP Rep. 2023 Aug 16;5(11):100876.
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