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Chemical Structure : C10M
Catalog No.: PC-21057Not For Human Use, Lab Use Only.
C10M is a small molecule inhibitor of C-reactive protein (CRP), inhibits the binding of pCRP to the physiological ligand phosphocholine (PC) with IC50 of 1.5 mM in ELISA assays.
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C10M is a small molecule inhibitor of C-reactive protein (CRP), inhibits the binding of pCRP to the physiological ligand phosphocholine (PC) with IC50 of 1.5 mM in ELISA assays.
C10M inhibits CRP-induced monocyte adhesion, expression of pro-inflammatory cytokines, and formation of platelet-leukocyte aggregates was evaluated in-vitro.
C10M inhibits pCRP binding to activated platelets and microvesicles and reduces pCRP*/mCRP induced ICAM-1 and VCAM-1 expression on human endothelial cells and activation of leukocytes.
C10M inhibits CRP-induced aggravation of renal ischemia/reperfusion injury, inhibits pCRP*/mCRP-induced aggravation of allograft rejection in a hindlimb transplantation model.
| M.Wt | 251.31 | |
| Formula | C11H26NO3P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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