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C450-0730

Chemical Structure : C450-0730

CAS No.: 1036730-46-7

C450-0730

Catalog No.: PC-62656Not For Human Use, Lab Use Only.

C450-0730 is a potent LuxN antagonist that antagonizes LuxN-AI-1 binding with IC50 of 2.7 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

C450-0730 is a potent LuxN antagonist that antagonizes LuxN-AI-1 binding with IC50 of 2.7 uM; competes for the AI-1 binding site of LuxN; inhibition for mutant LuxN G271D, R245L, and S184N is similar to that required to inhibit wild-type LuxN.

Physicochemical Properties

M.Wt 478.004
Formula C23H28ClN3O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((1-acetylindoline)-5-sulfonamido)-N-(4-chlorobenzyl)-4-methylpentanamide

References

1. Swem LR, et al. Cell. 2008 Aug 8;134(3):461-73.

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