C67-47

Chemical Structure : C67-47

Catalog No.: PC-27321Not For Human Use, Lab Use Only.

C67-47 is a potent and orally efficacious Phosphoglycerate kinase 1 (PGK1) inhibitor, binds strongly to PGK1 with a dissociation constant (Kd) of 63 nM, exhibits potent antiproliferative effects in pancreatic cancer cells.

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Biological Activity

Physicochemical Properties

M.Wt	403.47
Formula	C18H17N3O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-cyclohexyl-5-oxo-1-thioxo-4,5-dihydro-1H-[1,3]dioxolo[4,5-g]thiazolo[3,4-a]quinazoline-3-carboxamide

References

1. Lihua Liu, et al. J Med Chem. 2026 Jun 11;69(11):12955-12972.

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C67-47

Biological Activity

Physicochemical Properties

References

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