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Chemical Structure : CBLC000
Catalog No.: PC-72241Not For Human Use, Lab Use Only.
CBLC000 (CBL0100) is a small molecule histone chaperone FACT inhibitor, activates p53 and inhibits NF-κB with EC50 of 0.06 and 0.03 uM in cell-based p53 and NF-κB reporter assays, respecitvely.
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CBLC000 (CBL0100) is a small molecule histone chaperone FACT inhibitor, activates p53 and inhibits NF-κB with EC50 of 0.06 and 0.03 uM in cell-based p53 and NF-κB reporter assays, respecitvely. CBLC000 blocks emergence of iPSC colonies from primary MEFs, does not affect either the growth or undifferentiated state of established pluripotent cells.
| M.Wt | 374.484 | |
| Formula | C24H26N2O2 | |
| Appearance | Solid | |
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1. Alexander V Gasparian, et al. Sci Transl Med. 2011 Aug 10;3(95):95ra74.
2. Zuolian Shen, et al. Stem Cells Dev. 2018 Dec 15;27(24):1693-1701.
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