Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : CCT 365623 hydrochloride
CAS No.: 2126136-98-7
Catalog No.: PC-61190Not For Human Use, Lab Use Only.
CCT 365623 (CCT365623) hydrochloride is a potent, orally active small molecule inhibitor of lysyl oxidase (LOX) with IC50 of 0.89 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $328 | In stock | |
| 5 mg | $548 | In stock | |
| 10 mg | $898 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
CCT 365623 (CCT365623-) hydrochloride is a potent, orally active small molecule inhibitor of lysyl oxidase (LOX) with IC50 of 0.89 uM.
CCT 365623 inhibits LOX actvity in living cell system (MDCK cysts) at 5 uM, reduces EGFR retention at the cell surface, suppresses EGFR and AKT phosphorylation driven by EGF.
CCT 365623 also activates SMAD2 and downregulates MATN2.
CCT 365623 delays the growth of primary and metastatic tumour cells in vivo.
| M.Wt | 443.975 | |
| Formula | C18H18ClNO4S3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(5-((5-(methylsulfonyl)-[1,1'-biphenyl]-3-yl)sulfonyl)thiophen-2-yl)methanamine hydrochloride |
|
1. Tang H, et al. Nat Commun. 2017 Apr 18;8:14909.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
