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CD73 inhibitor Compound 73

Chemical Structure : CD73 inhibitor Compound 73

CAS No.: 2412019-98-6

CD73 inhibitor Compound 73

Catalog No.: PC-27237Not For Human Use, Lab Use Only.

CD73 inhibitor Compound 73 is a potent and selective non-nucleotide small molecule inhibitor of CD73 (ecto-5′-nucleotidase, eN) with IC50 of 12 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CD73 inhibitor Compound 73 is a potent and selective non-nucleotide small molecule inhibitor of CD73 (ecto-5′-nucleotidase, eN) with IC50 of 12 nM.

Physicochemical Properties

M.Wt 434.44
Formula C24H15FN8
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-({5-[4-fluoro-1-(2H-indazol-6-yl)-1H-1,2,3-benzotriazol-6-yl]-1H-pyrazol-1-yl}methyl)benzonitrile

References

1. Joel W Beatty, et al. J Med Chem. 2020 Apr 23;63(8):3935-3955.

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