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Chemical Structure : CH-5450
CAS No.: 252557-97-4
Catalog No.: PC-45053Not For Human Use, Lab Use Only.
A potent, peptide-inhibitor of human chymase with Ki of 1 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock |
Bulk size, bulk discount!
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A potent, peptide-inhibitor of human chymase with Ki of 1 nM; causes an almost complete inhibition of the AI-induced contractions combined with Enalaprilat; depresses the (Pro11-,D-Ala12)-AI-induced contractions at 10 uM.
| M.Wt | 652.7346 | |
| Formula | C34H44N4O9 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 43 mg/mL |
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| Chemical Name/SMILES |
L-Phenylalanine, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-L-prolyl-, 4-methyl ester |
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1. Bastos M, et al. Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):6738-42.
2. Waldeck K, et al. Br J Pharmacol. 1997 Jul;121(6):1081-6.
3. He S, et al. J Pharmacol Exp Ther. 1999 Nov;291(2):517-23.
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