CHET3

Chemical Structure : CHET3

CAS No.: 2489231-47-0

Catalog No.: PC-26570Not For Human Use, Lab Use Only.

CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels, including TASK-3 homomers and TASK-3/TASK-1 heteromers, displayspotent analgesic effects.

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Biological Activity

CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels, including TASK-3 homomers and TASK-3/TASK-1 heteromers, displayspotent analgesic effects.

Physicochemical Properties

M.Wt	423.49
Formula	C21H21N5O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-(4-oxo-6-((p-tolylthio)methyl)-1,4-dihydropyrimidin-2-yl)guanidine

References

1. Liao P, et al. Sci Transl Med. 2019 Nov 20;11(519):eaaw8434.

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CHET3

Biological Activity

Physicochemical Properties

References

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