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Chemical Structure : CIB-3b
Catalog No.: PC-38904Not For Human Use, Lab Use Only.
CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells.
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CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells.
CIB-3b directly binds to transactivation response (TAR) RNA-binding protein 2 (TRBP), altering the activity of Dicer and mature miRNA production.
| M.Wt | 261.277 | |
| Formula | C14H15NO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ting Peng, et al. J. Med. Chem. 2022
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