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Chemical Structure : CID 2745687
CAS No.: 264233-05-8
Catalog No.: PC-38606Not For Human Use, Lab Use Only.
CID-2745687 is a potent, selective and competitive GPR35 antagonist with pIC50 of 6.7 against human GPR35.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 100 mg | Get quote |
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CID-2745687 is a potent, selective and competitive GPR35 antagonist with pIC50 of 6.7 against human GPR35.
CID-2745687 competitively inhibited the effects at human GPR35 of cromolyn disodium and zaprinast, two agonists that share an overlapping binding site.
CID-2745687 blocked zaprinast-promoted VSMC migration in the scratch-wound assay.
| M.Wt | 395.429 | |
| Formula | C17H19F2N5O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
methyl-5-[(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate |
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1. Jenkins L, et al. J Pharmacol Exp Ther. 2012 Dec;343(3):683-95.
2. McCallum JE, et al. J Vasc Res. 2015;52(6):383-95.
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