Catalog No.: PC-62458Not For Human Use, Lab Use Only.
CK-666 (CK 0944666) is a small molecule Arp2/3 complex inhibitor with IC50 of 4 uM, inhibits actin polymerization with either BtArp2/3 complex (IC50=17 uM) or SpArp2/3 complex (IC50=5 uM).
CK-666 (CK 0944666) is a small molecule Arp2/3 complex inhibitor with IC50 of 4 uM, inhibits actin polymerization with either BtArp2/3 complex (IC50=17 uM) or SpArp2/3 complex (IC50=5 uM).
CK-666 reduces actin polymerization around intracellular Listeria to background levels at lower concentrations than CK-636.
CK-666 alters the morphology and slightly slowed but did not stop the gliding motility of fish keratocytes
