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Cat. No. Product Name CAS No. Information
PC-44784

CK-636

442632-72-6

A small molecule Arp2/3 complex inhibitor that inhibits actin polymerization stimulated by fission yeast Arp2/3 complex (SpArp2/3 complex, IC50 = 24 uM); inhibits formation of actin filament comet tails by Listeria and podosomes by monocytes.

PC-62459

CK 869

388592-44-7 CK 869 is an inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex, inhibits actin polymerization (IC50=11 uM); does not inhibit budding or fission yeast Arp2/3 complexes.
PC-62458

CK 666

442633-00-3 CK 666 (CK 0944666) is a small molecule Arp2/3 complex inhibitor with IC50 of 4 uM, inhibits actin polymerization with either BtArp2/3 complex (IC50=17 uM) or SpArp2/3 complex (IC50=5 uM); reduces actin polymerization around intracellular Listeria to background levels (Fig. 2e and g) at lower concentrations than CK-636; alters the morphology and slightly slowed but did not stop the gliding motility of fish keratocytes

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