You are here:Home-Chemical Inhibitors & Agonists-Apoptosis-MDM2-p53-CP-31398 dihydrochloride
CP-31398 dihydrochloride

Chemical Structure : CP-31398 dihydrochloride

CAS No.: 1217195-61-3

CP-31398 dihydrochloride (CP31398 dihydrochloride)

Catalog No.: PC-62082Not For Human Use, Lab Use Only.

CP-31398 is a small molecule p53 reactivator that protects p53 from thermal denaturation, not only reactivates mutant p53 but also induces stabilization of wild type p53.

Packing Price Stock Quantity
100 mg Get quote
250 mg Get quote
500 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CP-31398 is a small molecule p53 reactivator that protects p53 from thermal denaturation, not only reactivates mutant p53 but also induces stabilization of wild type p53; shows anti-tumor activity in vivo in a transgenic UPII-SV40T mouse model of bladder transitional cell carcinoma.

Physicochemical Properties

M.Wt 435.39
Formula C22H26N4O.2HCl
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride

References

1. Foster BA, et al. Science. 1999 Dec 24;286(5449):2507-10.

2. Madka V, et al. Neoplasia. 2013 Aug;15(8):966-74.

3. Wang W, et al. Mol Cell Biol. 2003 Mar;23(6):2171-81.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: