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Chemical Structure : CPT157633
Catalog No.: PC-35178Not For Human Use, Lab Use Only.
CPT157633 is a novel potent, selective PTP1B inhibitor with Ki of 40 nM, shows markedly less activities against a panel of 6 PTPs and 2 dual-specificity phosphatases.
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CPT157633 is a novel potent, selective PTP1B inhibitor with Ki of 40 nM, shows markedly less activities against a panel of 6 PTPs and 2 dual-specificity phosphatases.
CPT157633 prevents binge drinking-induced glucose intolerance in vivo.
CPT157633 also ameliorates the X-linked neurological disorder Rett syndrome (RTT) phenotypes in male mouse models.
| M.Wt | 465.203 | |
| Formula | C12H16BrF2N2O6PS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lindtner C, et al. Sci Transl Med. 2013 Jan 30;5(170):170ra14.
2. Krishnan N, et al. J Clin Invest. 2015 Aug 3;125(8):3163-77.
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