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Chemical Structure : CQ211
Catalog No.: PC-38737Not For Human Use, Lab Use Only.
CQ211 is a potent, highly selective RIOK2 inhibitor with Kd of 6.1 nM, shows excellent selectivity to RIOK2 in both enzymatic and cellular assays.
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CQ211 is a potent, highly selective RIOK2 inhibitor with Kd of 6.1 nM, shows excellent selectivity to RIOK2 in both enzymatic and cellular assays.
CQ211 exhibits potent proliferation inhibition activity against multiple cancer cell lines (HT20, cell IC50=0.38 uM) and demonstrates promising in vivo efficacy in mouse xenograft models.
| M.Wt | 521.504 | |
| Formula | C26H22F3N7O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yifan Ouyang, et al. J Med Chem. May 18, 2022.
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