Chemical Structure : CRT-0105950
CAS No.:
1661845-86-8
CRT-0105950
(CRT0105950)
Catalog No. : PC-70101Not For Human Use, Lab Use Only.
CRT-0105950 (CRT0105950) is a novel potent LIMK inhibitor with IC50 of 0.3 nM and 1 nM for LIMK1 and LIMK2, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-7010101
Biological Activity
CRT-0105950 (CRT0105950) is a novel potent LIMK inhibitor with IC50 of 0.3 nM and 1 nM for LIMK1 and LIMK2, respectively.
Physicochemical Properties
M.Wt
393.889
Formula
C21H16ClN3OS
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-((5-(3-(2-chloro-4-methylphenyl)pyridin-4-yl)thiazol-2-yl)amino)phenol
References
1. Mardilovich K, et al. Oncotarget
2. Charles MD, et al. J Med Chem
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