CSH-4044 | PIM/DYRK inhibitor | Probechem Biochemicals

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Chemical Structure : CSH-4044

CSH-4044 (CSH4044)

Catalog No.: PC-25793Not For Human Use, Lab Use Only.

CSH-4044 is a specific, dual PIM and DYRK families of kinases inhibitor, reduces Tau phosphorylation at three residues, Tau S212, S202/T205 and T231, suppresses PIM3-driven BAD phosphorylation in pancreatic cancer cells and reduced DYRK1A-mediated Tau phosphorylation in neuronal cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	347.34
Formula	C16H13NO6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(2,5-dihydroxy-4-methoxyphenyl)(6-hydroxy-5-methoxybenzo[d]thiazol-2-yl)methanone

References

1. Gyula Bencze, et al. bioRxiv [Preprint]. 2025 Oct 23:2025.10.22.683941.

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CSH-4044 (CSH4044)

Biological Activity

Physicochemical Properties

References

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