Cat. No. |
Product Name |
Information |
PC-35492 |
HS56
Pim/DAPK3 inhibitor
|
HS56 (Pim-DAPK3 inhibitor HS56) is a potent, dual Pim/DAPK3 inhibitor with Ki of 72 nM (Pim-3) and 315 nM (DAPK3), shows micromolar potency toward Pim-1 and Pim-2 (Ki=1.5 and 17 uM). |
PC-63507 |
SEL24-B489
PIM/FLT3-ITD inhibitor
|
SEL24-B489 (SEL24, MEN1703) is a potent, dual PIM and FLT3-ITD inhibitor with Kd of 2/2/3 nM for PIM1/2/3, Kd of 160/16 nM for FLT3-WT/FLT3-ITD, respectively. |
PC-43464 |
SGI-1776
Pim inhibitor
|
SGI-1776 is a potent, selective, orally active Pim kinase inhibitor with IC50 of 7, 363 and 69 nM for Pim1, Pim2 and Pim3, respectively. |
PC-63142 |
JP-11646
Pim2 inhibitor
|
JP-11646 is a novel potent, selective, non-ATP competitive Pim2 inhibitor with IC50 of 0.5/1/24 nM for Pim2/3/1, respectively. |
PC-63141 |
NMS-P645
Pim inhibitor
|
NMS-P645 is a potent, selective inhibitor of pan-Pim kinases with IC50 of 3/73/12 nM for Pim1/2/3, respectively. |
PC-70113 |
LGB-321
Pim inhibitor
|
LGB-321 (LGB321) is a potent and specific pan-Pim inhibitor with Ki of 1/2.1/0.8 pM for Pim1/2/3, respectively. |
PC-45415 |
CX-6258
pan-Pim inhibitor
|
CX-6258 (CX6258) is a potent, selective, and orally efficacious pan-Pim inhibitor with IC50 of 5/25/16 nM for Pim1/2/3, respectively. |
PC-45110 |
GDC-0339
|
GDC-0339 (GDC0339) is a novel small molecule pan-Pim kinase inhibitor that was discovered as a potential treatment for multiple myeloma. |
PC-45606 |
PIM-447 dihydrochloride
Pim inhibitor
|
PIM-447 (LGH-447) dihydrochlorid is a highly potent and selective inhibitor of pan-Pim with IC50s of 6/18/9 pM for Pim/1/2/3 respectively. |
PC-45605 |
PIM-447
Pim inhibitor
|
PIM-447 (LGH-447) is a highly potent and selective inhibitor of pan-Pim with IC50s of 6/18/9 pM for Pim/1/2/3 respectively. |
PC-38740 |
pan-PIM inhibitor 27
Pim inhibitor
|
pan-PIM inhibitor 27 (SARxxxx92) is a potent, selective, orally bioavailable pan-PIM kinase inhibitor with IC50 of 1, 6 nM for Pim1 and Pim2, respectively. |
PC-38739 |
DHPCC-9
Pim inhibitor
|
DHPCC-9 is a selective Pim kinase inhibitor, inhibits Pim-1-dependent survival of cytokine-deprived myeloid cells (IC50=4-6 uM). |