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Chemical Structure : CSIC E379
Catalog No.: PC-62437Not For Human Use, Lab Use Only.
CSIC E379 is a potent, selective uncoupling proteins UCP1/UCP2 inhibitor with EC50 of 20 uM/30 uM, respectively.
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CSIC E379 is a potent, selective uncoupling proteins UCP1/UCP2 inhibitor with EC50 of 20 uM/30 uM, respectively; does not affect OXPHOS system and membrane permeability in liver mitochondria; causes oxidative stress, inhibit the cellular respiration of the cancer cell line HT-29; increases the production of superoxide and decreases the cell viability; potentiates the efficacy of the cytotoxic drug arsenic trioxide.
| M.Wt | 280.411 | |
| Formula | C20H24O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Rial E, et al. Chem Biol. 2011 Feb 25;18(2):264-74.
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