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Chemical Structure : CU239
Catalog No.: PC-63457Not For Human Use, Lab Use Only.
CU239 is a novel non-retinoid RPE65 inhibitor that selectively inhibits isomerase activity of RPE65 with IC50 of 6 uM.
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CU239 is a novel non-retinoid RPE65 inhibitor that selectively inhibits isomerase activity of RPE65 with IC50 of 6 uM; CU239 inhibits RPE65 via competition with its substrate all-trans-retinyl ester; suppresses visual cycle and prevents retinal degeneration in mice.
| M.Wt | 436.409 | |
| Formula | C19H15F3N4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Shin Y, et al. Biochim Biophys Acta. 2018 Apr 21. pii: S0925-4439(18)30146-7.
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