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Chemical Structure : CUDA
Catalog No.: PC-70252Not For Human Use, Lab Use Only.
A potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.
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A potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively; blocks conversion of 1 uM 14,15-EET to 14,15-DHET by 94% at 10 uM in COS-7 cells; activates PPARα 8-fold at a concentration of 10 uM but exhibits no affect on PPARδ or PPARγ.
| M.Wt | 340.5 | |
| Formula | C19H36N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Morisseau C, et al. Biochem Pharmacol. 2002 May 1;63(9):1599-608.
2. Fang X, et al. J Pharmacol Exp Ther. 2005 Jul;314(1):260-70.
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