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CW3388

Chemical Structure : CW3388

CAS No.: 414881-01-9

CW3388 (CW-3388, CW-3388)

Catalog No.: PC-72961Not For Human Use, Lab Use Only.

CW3388 (CW-3388, CW3388) is a potent, cell-active Δ8,7-sterol isomerase (EBP) inhibitor, shows near-maximal effects on oligodendrocyte formation at 110 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CW3388 (CW-3388, CW3388) is a potent, cell-active Δ8,7-sterol isomerase (EBP) inhibitor, shows near-maximal effects on oligodendrocyte formation at 110 nM.
CW3388 treatment substantially increased the area of microfibers tracked by MBP+ oligodendrocytes.
CW3388 treatment promotes both MBP+ oligodendrocyte formation and subsequent myelination in oligodendrocyte progenitor cells (OPCs).

Physicochemical Properties

M.Wt 279.427
Formula C20H25N
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-([1,1'-biphenyl]-4-ylmethyl)azocane

References

1. Dharmaraja Allimuthu, et al. Cell Chem Biol. 2019 Apr 18;26(4):593-599.e4.

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