CaMKII-IN-1 |CAS:1208123-85-6 Probechem Biochemicals

Chemical Structure : CaMKII-IN-1

CAS No.: 1208123-85-6

CaMKII-IN-1 (CaMKII inhibitor)

Catalog No.: PC-45443Not For Human Use, Lab Use Only.

CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM.

Packing	Price	Stock
5 mg	$138	In stock
10 mg	$228	In stock
25 mg	$398	In stock
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Biological Activity

CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM.
CaMKII-IN-1 shows no inhibitory effect for CaMKIV, MLCK, p38α, Akt1, PKC etc.
CaMKII-IN-1 shows 25-fold higher potency than KN-93.

Physicochemical Properties

M.Wt	548.0988
Formula	C29H30ClN5O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 54 mg/mL
Chemical Name/SMILES	Benzenesulfonamide, 3-chloro-2-methyl-N-[5,6,7,8-tetrahydro-2-[(2-phenylethyl)amino]-6-(phenylmethyl)pyrido[4,3-d]pyrimidin-4-yl]-

References

1. Asano S, et al. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6696-8.

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CaMKII-IN-1 (CaMKII inhibitor)

Biological Activity

Physicochemical Properties

References

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