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Chemical Structure : Candoxatrilat
Catalog No.: PC-60711Not For Human Use, Lab Use Only.
A potent neutral endopeptidase EC 3.4.24.11 (atriopeptidase) inhibitor that increases endogenous ANF levels and produces natriuretic and diuretic responses intravenously in mice..
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A potent neutral endopeptidase EC 3.4.24.11 (atriopeptidase) inhibitor that increases endogenous ANF levels and produces natriuretic and diuretic responses intravenously in mice.
Heart Failure
Phase 1 Discontinued
| M.Wt | 399.484 | |
| Formula | C20H33NO7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Danilewicz JC, et al. Biochem Biophys Res Commun. 1989 Oct 16;164(1):58-65.
2. Shepperson NB, et al. Br J Pharmacol. 1989 Dec;98 Suppl:822P.
3. Jardine AG, et al. Am J Hypertens. 1990 Sep;3(9):661-7.
4. Northridge DB, et al. Lancet. 1989 Sep 9;2(8663):591-3.
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