Carbamazepine | Sodium channel blocker, HDAC inhibitor

Chemical Structure : Carbamazepine

CAS No.: 298-46-4

Carbamazepine (NSC 169864)

Catalog No.: PC-27929Not For Human Use, Lab Use Only.

Carbamazepine (NSC 169864) is an orally active pressure-sensitive sodium ion channel blocker, blocks voltage gated Na+, Ca2+, and K+ channels, and is also a HDAC inhibitor (IC50=2 uM), is an anticonvulsant.

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Biological Activity

Physicochemical Properties

M.Wt	236.27
Formula	C15H12N2O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5H-Dibenzo[b,f]azepine-5-carboxamide

References

1. Willow, M, et al. Mol Pharmacol, 1982. 22(3): p. 627-35.

2. Okada, M., et al. Epilepsy Res, 1997. 28(2): p. 143-53.

3. Beutler AS, et al. Life Sci. 2005 May 13;76(26):3107-15.

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Carbamazepine (NSC 169864)

Biological Activity

Physicochemical Properties

References

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