Carbonic anhydrase inhibitor C18

Chemical Structure : Carbonic anhydrase inhibitor C18

Catalog No.: PC-24454Not For Human Use, Lab Use Only.

Carbonic anhydrase inhibitor C18 is a potent carbonic anhydrase inhibitor with Ki values of 4000, 21, 60, 14 and 7.0 nM for isozymes hCA I, hCA II, hCA IV, hCA IX, and hCA XII respectively.

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Biological Activity

Carbonic anhydrase inhibitor C18 is a potent carbonic anhydrase inhibitor with Ki values of 4000, 21, 60, 14 and 7.0 nM for isozymes hCA I, hCA II, hCA IV, hCA IX, and hCA XII respectively.

Physicochemical Properties

M.Wt	404.86
Formula	C16H21ClN2O6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate

References

1. Alterio V., et al. J. Enzym. Inhib. Med. Chem. 2018;33:151–157.

2. Amiranda S, et al. Heliyon. 2025 Feb 5;11(4):e42457.

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